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Calling them interchangeable because they share a primary target is like saying a scalpel and surgical scissors are the same tool because they both cut

Redox control of non-shivering thermogenesis

For targeting alveolar macrophages, mannose is widely utilized owing to its interaction with the macrophage mannose receptor 1 (also known as CD206) on macrophage surfaces, making it a popular choice in pulmonary drug delivery applications 221,222 , including LNPs 223 , solid LNPs 223,224 and other lipid nanoformulations 225

Alternatively, a combination of CB1 and GHSR1a agonists could be used to increase appetite and decrease nausea, for instance, in patients undergoing chemotherapy