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GLP-1 agonists like semaglutide help lower blood sugar levels by increasing the amount of insulin released by the pancreas and decreasing the amount of glucose produced by the liver, notes Chris Damman, M.D., clinical associate professor of Gastroenterology and Medicine at the University of Washington and the chief medical officer of supplement company Supergut

Injections bypass the gut, and for these patients treatment is often a long-term maintenance strategy guided by their provider

Most patients receive initial instruction from a practice nurse or healthcare professional before attempting home administration

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