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Estonian microbiologists at the University of Tartu first discovered the amazing antioxidant potential of ME-3 in 1995

reported a decreased incidence of G6PD-d in patients presenting to the hospital for coronary artery disease, though the sample size of G6PD-d patients was again limited and the case control design has more limitations when compared to retrospective cohort studies 17

It is a double-blind, placebo-controlled Phase 2 study enrolling 120 participants

Assessment of antioxidant enzyme activities and oxidative stress markers To assess antioxidant enzyme activities and oxidative stress markers, frozen-thawed spermatozoa of each group (repeated in triplicated) were collected and centrifuged at 800g for 20 min to separate spermatozoa from seminal plasma