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doi: 10.3389/fpls.2016.00259 11 YinLChenCChenGCaoBLeiJ

There are currently ongoing clinical trials in humans with osteoarthritis of the knee, hip and shoulder where AOD 9064 + HA is being studied for its effects in osteoarthritis

Due to the unique characteristics of hypoxia, acidification, and inflammation within the TME, the antitumor effects of cytotoxic T lymphocytes (CTL), natural killer cells (NK), and dendritic cells (DC) are inhibited