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Description

Surg., 17 May 2024 Sec

Importantly, the expression of these genes is controlled by the transcription factor NRF2, and, in fact, the level of this protein was highly reduced in the most sensitive cell line, NCI H23, explaining the reduced expression of genes involved in GSH synthesis (Fig

However, excessive NAC administration may paradoxically trigger seizures, potentially due to its modulatory effects on the glutamatecysteine antiporter system