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Endothelial cell dysfunction results in ECM metabolism disorders, VSMC apoptosis, aortic wall thinning, and then aortic aneurysms and dissection

They also support liver health, which is essential for effectively metabolizing fats

Pre-publication history The pre-publication history for this paper can be accessed here: Acknowledgements Funding for logistical assistance such as publication costs was provided by the Cyclic Vomiting Syndrome Association Additional information Competing interests The author declares that they have no competing interests

4 Causes and Risk Factors It is currently widely accepted that IPF is the result of a combination of environmental and genetic predisposition to increased fibrotic activity, setting the stage for repeated micro-injuries to an aging alveolar lining and triggering dysfunctional signaling between the alveolar cells and fibroblasts (Fois 2018