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This combination therapy not only effectively disrupts the metabolic adaptation caused by TP53 mutations but also provides a new direction for the treatment of CRPC and other prostate cancers by targeting key metabolic pathways

Nat Cell Biol (2019) 21(1):6371

Microglia are key players in this regulation, affecting both long-term potentiation (LTP) and long-term depression (LTD), which are fundamental mechanisms underlying synaptic plasticity (Raghuraman et al., 2019