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Safety Profile Across all six human trials and the extensive preclinical work, the safety picture is quite clean: No serious adverse events attributed to the compound No effect on IGF-1 No impairment of glucose tolerance or insulin sensitivity No genotoxic activity Most common side effects: mild injection site irritation, occasional headache or fatigue all transient This is genuinely one of the better-characterized peptides from a safety standpoint, largely because it actually went through a formal development process with proper clinical oversight

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In A and B, two independent experiments are shown

BPC-157s research base is anchored in the work of Sikiric and colleagues at the University of Zagreb, who have published extensively on the peptide since the early 1990s