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Determination of prolactin: the macroprolactin problem

Although ABM domains were initially discovered (and named) for their roles in antibiotic biosynthesis 43 , they have since been shown to play more diverse roles in cellular metabolism with the discovery of their involvement in the enzymatic degradation of heme 52,53

Thus, our data strongly suggest that the local injection of IKE + DHAA induce ferroptosis in vivo in the tumor area and could have highly beneficial effects for the eradication of highly aggressive tumors

They target distinct biological pathways, which is precisely why their combination (CagriSema) is under investigation offering broader metabolic coverage than either agent individually