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Therefore, more research should explore the role TIMP-2 and MMP-2 may have in PTSD, and how they not only relate to central oxidative stress processes, but common somatic comorbidities in PTSD as well

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Independent studies in 2014 demonstrated that mtDNA is released during mitochondrial apoptosis (99), and subsequent research indicated that apoptosis-associated mitochondrial outer membrane permeabilization plays a crucial regulatory role in mtDNA release (100)