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Toxicol Lett 123(23):227234

However, factors like UV radiation, pollution, and stress can create excess free radicals

Current pharmacogenetic perspective on Stevens-Johnson Syndrome and toxic epidermal necrolysis

Aging causes changes in the cochlear tissue structure, including thickening of the basilar membrane, weakening of the elasticity of the spiral ligaments, and narrowing and hardening of the blood vessels, leading to impaired sound conduction, ischemia, and hypoxia in the cochlea