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Rescue therapy was needed by 8%, 25%, and 67%, respectively. Five milligrams preserved most, but not all, of the benefit of continuing the effective dose

Small molecules that deplete glutathione levels are referred to as Class I ferroptosis-inducing compounds (FINs), while those that cause ferroptosis through direct inhibition of GPX4 without depleting glutathione are termed Class II FINs

PMID: 39747971 Brain Res Bull Nerol ameliorates cognitive dysfunction in vascular dementia rats by inhibiting mitochondrial oxidative stress and reducing hippocampal senescence