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In more recent studies, it has been suggested that elevated epoxide hydroxylases in the brain could contribute to neuroinflammation observed in AD (Ghosh et al., 2020)

In HCT116 and MDA-MB-231 breast cancer cells, royal jelly acid reduced histone deacetylase enzyme levels, promoting chromatin lysine residue acetylation and triggering an increase in gene expression levels ( in vitro experiments are required

Systemic exposure to the CYP3A-mediated metabolites 1-hydroxymidazolam and 4-hydroxymidazolam also increased (AUC inf , ~1827%) but by a smaller magnitude compared with midazolam

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