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10.1001/jamadermatol.2021.2007 197

Following translocation of newly formed Nrf2 to the nucleus, KEAP1 mRNA levels, total Keap1 protein concentrations and Keap1 concentrations in the autophagosome increase

In addition, sulforaphane is an HDAC inhibitor used to treat colorectal cancer that can inhibit tumor progression by targeting HDAC1 and HDAC2 [353, 354]

While glutathione is not a treatment for acne, it is commonly used as part of broader skin wellness routines that focus on overall skin health and appearance