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Superimposition of the hTrx1 structures obtained in the hTrxR1hTrx1 complexes with published structures in the uncomplexed form (PDB codes 2hsh 18 , and 1aiu 17 ) also shows r.m.s

Annu Rev Neurosci 31:175193 Brys M, Fanning L, Hung S, Ellenbogen A, Penner N, Yang M, Welch M, Koenig E, David E, Fox T (2019) Randomized phase I clinical trial of anti-synuclein antibody BIIB054

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This is true for the adrenal cortex, epithelial cells lining cavities (colon mucosal cells, cells of kidney tubular epithelium, placental trophoblasts) and also for endothelial cells of the brain and testicular capillaries