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Despite a general decrease in antioxidant markers in the serum, SOD and GPx increased in the AH, likely as a protective response in the eye against oxidative stress ( In general, discrepancies between expression level and enzymatic activity are not infrequent, and they are not limited to compensatory mechanisms, where the decreased activity of a given enzyme (due to an age-related impairment of the biological system or any more specific cause) may be counterbalanced by an increase in its expression

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