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(100) demonstrated decreased 24-hour GH secretion despite the mean IGF-I SDS being +1.0 in patients with Cushings disease, and Bang et al

The increased expression of nicotinamide adenine dinucleotide phosphate (NADPH) oxidases in cancer cells leads to higher levels of intracellular ROS, which supports survival and lessens radiation sensitivity

It could effectively silence the expression of circMAP2K2 (hsa_circRNA_102415), thereby inhibiting the epithelial-mesenchymal transition (EMT)-like phenotype generated by circMAP2K2 through the protease-mediated PCBP1/GPX1 axis, inhibiting the activated AKT/GSK3 signaling pathway and achieving the goal of inhibiting the proliferation and metastasis of gastric cancer cells, which provides a new tool for the treatment of gastric cancer (52)

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