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Acquisition of BL tolerance in SL via adaptive obesitywhen specific bacteria are implicated in host fitness-related phenotypes, their relative enrichment often leads to reduced microbiota diversity 33,68

In solid tumors, oxygen levels may be reduced (due to local hypoxia) and therefore the efficiency of PDT, especially of type II reactions, can be limited 62,64

Table 30 in the CY 2025 PFS proposed rule (89 FR 61861), which is the same as the following Table 33, lists the Medicare CQMs in the APP Plus quality measure set that would be eligible for flat benchmarks in performance year 2025 through performance year 2029 under our proposal