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For evaluating its future clinical use as a therapeutic drug and follow-up clinical trials, the present study was undertaken to evaluate the pharmacokinetics, tissue distribution, metabolism, and drug excretion of BPC157 in Sprague-Dawley (SD) rats and beagle dogs as well as in associated in vitro studies

Using recommended dosing conditions for oral semaglutide, mean bioavailability was estimated at approximately 0.8% (0.795% [95% confidence interval 0.7360.864]) (Table 1 of the ESM)

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