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S2CID 85179401

Vitamin C deficiency causes oxidative damage to macromolecules (lipids, proteins) in the brain (13)

The role of mitochondrial dysfunction during bipolar disorder is supported both by observation of the changes of brain metabolism and by effects of mood stabilizers (lithium and valproate) on mitochondrial functions

These findings, although obtained from models of oxidative stress and mitochondrial dysfunction rather than in autism models, are highly relevant because they target biological mechanism that are also characteristic of ASD (Sachdeva et al., 2022)