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Its primary actions include: Increasing slow-wave (delta) sleep the deepest, most physically restorative sleep stage Modulating corticotropin-releasing hormone (CRH) reducing the HPA axis signalling that keeps cortisol elevated Influencing LH and somatostatin release both relevant to testosterone and growth hormone secretion Antioxidant activity preclinical data suggests DSIP has direct free-radical scavenging properties (3) Thermoregulatory effects potentially lowering basal body temperature in a manner consistent with natural sleep onset The net effect is not sedation

It begins in the lower back and extends through the buttocks down the back of each leg to the thighs and feet

It is particularly relevant for patients whose training produces diffuse connective tissue stress across multiple joints simultaneously, which is common in athletes running compound movements at high volumes

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