The sodC and sodB sodC mutants were also significantly attenuated for virulence in intranasally challenged C57BL/6 mice compared to the wild-type LVS, indicating that SOD-C is required for resisting host-generated ROS and contribute to survival and virulence of in mice [119]
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These may be due to dietary problems, either related to malnutrition and intestinal diseases or to poor dietary education (such as the Western diet)