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4.1.2 Iron overload promotes joint ferroptosis by disrupting gut barrier Imbalanced host iron homeostasis remodels the structure of the gut microbiota, which can be manifested as changes in alpha-diversity, alterations in taxonomy composition and community dominance (Mao et al., 2024)

Because it does not cross the blood-brain barrier easily and acts primarily on peripheral fat tissue, it is viewed as a highly targeted fat-loss agent with minimal central nervous system side effects

In this way, B-12 supplementation can improve mitochondrial health and help combat weakened muscular function

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