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For example, in chronic cerebral hypoperfusion models, inhibited differentiation of OPCs, white matter damage, and cognitive deficits were all linked to impaired oligodendrocyte-astrocyte interactions mediated by BDNF, highlighting the importance of normal intercellular communication between OLs and other cells for cognitive function ( Certainly, the heterogeneity of OLs further complicates research efforts

Bilirubin and Enzyme Activity To determine the serum levels of aspartate transaminase (AST), alanine transaminase (ALT, IU/L), and total bilirubin (mol/L), blood samples were collected from the inferior caval vein immediately before euthanasia and were centrifuged for 15 min at 3000 rpm

Campa, A., Shor-Posner, G., Indacochea