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In particular, central myelin degeneration promoted by pathological interactions involving both peripheral and central cell-mediated immune attacks induces the accumulation of dysfunctional myelin and neurological deficits 1,11

Medication Adjustments If side effects remain problematic despite conservative measures, discuss with your physician options such as temporarily reducing the dose, extending time at current dose before escalating, or switching to the oral formulation which may have a different tolerability profile for some patients

Conjunction with each other, they act on slightly different mechanisms

In my three decades of direct observation and collaboration with leading clinicians, Ive seen consistent therapeutic responses with once-daily and twice-daily dosing protocols