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The average duration of treatment was 15 weeks (range 1020), with peak levodopa equivalent daily doses (LEDD) reaching 702 mg

PEG-MGF is associated with localized repair signaling, while IGF-1 LR3 is involved in systemic growth and anabolic processes

ACS Omega 9:2785327871 Sekar V, Al-Ansari MM, Narenkumar J et al (2022) Synthesis of gold nanoparticles (AuNPs) with improved anti-diabetic, antioxidant and anti-microbial activity from Physalis minima

Moreover, emerging evidence indicates that CNMs can be fermented by gut bacteria into bioactive metabolites like butyrate, which then modulate host physiology, such as intestinal stem cell differentiation highlighting not only toxicological but also transformative microbialhost interactions ( in vitro systems such as gut-on-chip platforms are increasingly integrated into tiered risk frameworks to enhance hazard identification without excessive animal use