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Upon HGF-induced activation of c-MET, phosphorylation at Y1003 recruits the E3 ubiquitin ligase CBL, leading to ubiquitination of c-MET

Molecular docking and structure-based drug design strategies

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Perioperative implications were evaluated with emphasis on orthopaedic surgical risk domains relevant to total joint arthroplasty (TJA), including wound complications, hematoma formation, immune modulation, infection susceptibility, heterotopic ossification, and implant fixation considerations