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The current text in the Boxed warning is FINTEPLA can cause valvular heart disease and pulmonary arterial hypertension. The change reflects the occurrence of cases of valvular heart disease and pulmonary arterial hypertension during use of fenfluramine in the postmarketing setting, mentioned in Section 5.1 (Warnings and Precautions

[DOI] [Google Scholar] 188.Bottaccioli F., Bottaccioli A.G

If you experience severed, throbbing pain, and extreme swelling, this is not a normal side effect of bruising and this will need immediate medical attention