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While they can be effective for mild deficiencies or maintenance once adequate levels are reached, they are generally not as effective as injections for treating severe deficiencies

2010 doi: 10.1371/journal.pone.0010667

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Functionally, GIP receptor activation improves intracellular Ca 2+ concentration, glucagon secretion, and cell depolarization by increasing cAMP/PKA signaling pathways [75, 76]