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polygyrus EVs were able to suppress macrophage responses and IL-33 signaling, and contained miRNAs that specifically targeted host DUSP1 RNA, a regulator of MAPK signaling ( Ascaris suum , which infects pigs, where miRNA sequence analysis predicted that they targeted the host Th2 immune response (IL-13, IL-25, IL-33) ( Litomosomoides sigmodontis -infected mice, O

Disruptions in this axis, such as those induced by ischemiareperfusion (I/R) injury in the intestine, have been implicated in a range of pathological outcomes, including cognitive dysfunction (Yang et al., 2020b)

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First, because the KNHANES is a cross-sectional survey, this study can confirm the association but cannot establish a causal relationship