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In hypertensive patients with normal renal function, therapeutic doses of amlodipine resulted in a decrease in renal vascular resistance and an increase in glomerular filtration rate and effective renal plasma flow without change in filtration fraction or proteinuria

310 A five-year, randomized, single-blind trial of patients with early-stage Parkinsons disease examined the effect of bilateral DBS of the subthalamic nucleus (STN) in combination with levodopa compared with levodopa alone

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