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Elamipretide reduces IPF-associated inflammation and fibrosis by inhibiting Nrf2-dependent NLRP3 inflammasome in macrophages (274)

Abdominal obesity, independent from caloric intake, accounts for the development of intestinal tumors in Apc(1638N/+) female mice

When mammalian cells experience irreversible disruptions in their internal or external milieu, they can initiate several signal transduction cascades that ultimately result in cell death (Kayagaki et al., 2024

Anti-inflammatory and antioxidant effects: GHK-Cu downregulates pro-inflammatory cytokines (like IL-6) and upregulates antioxidant enzymes (such as superoxide dismutase)