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Description

P.BeckE

Long-term data from the Swiss pulmonary hypertension registry

Embodiment 118 The antibody according to any one of embodiments 1-8, wherein said antibody comprises a heavy chain variable region (VH) of an M25ASIA antibody and a light chain variable region (VL) of an M25ASIA antibody

Nitrotyrosine within the infected, nitric oxide-generating macrophages, may be enhanced by GSH actions: (a) reducing the protein disulfides, and/or glutathionylating the free protein thiols allows for some unfolding, as intramolecular and interchain disulfides are reduced and/or glutathionylated