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B12 absorption requires a protein called intrinsic factor , produced in the stomach

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Further, though a rare complication, Wernickes Encephalopathy has been documented in multiple studies in association with hyperemesis graviderum and predisposition to vitamin deficiencies (alcoholism, chronic malnutrition) should be considered prior to starting dextrose-containing fluids.[17-20] Regarding pharmacological therapy for NVP, many expecting mothers and clinicians are understandably concerned about the potential impact any treatment modalities may have on the developing fetus

Experimental studies have shown a 30% increase in G0/G1 phase cell population and a 40% decrease in S phase cell population with hesperidin treatment, indicating cell cycle arrest in cancer cells