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reported that reduced gut microbial diversity and proinflammatory group expansion in patients with advanced cirrhosis were associated with reduced bile acid pools, and patients with UC experienced a similar phenomenon (109)

10.1038/s41390-018-0191-9 Pediatr

In IL-10 (/) mice, it alleviates colitis by reducing colonic lamina propria CD4+ T cells, lowering TNF- and IFN- levels, inhibiting epithelial cell apoptosis, increasing tight junction protein (occludin and ZO-1) expression, and enhancing intestinal barrier function [117]