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The former causes cerebral hemorrhage by decomposing collagen on the cell matrix and vascular basement membrane, which has the advantage of high efficiency and convenience

Vaccination with rEE2 and rMCP antigens induces memory recall responses The first vaccinated elephant (A) received 20% of the eventual viral dose of MVA and half of the g protein boost dose during the first rMVA-EE2-MCP prime and protein boost cycle to initially assess safety and determine the dose range, which was then increased in the second prime-boost cycle to the final dose used in the rest of the trial

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PMID 19403631