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doi: 10.1007/s10048-004-0181-4

Since these hormones also decrease with age, boosting growth hormone without balancing sex hormones may have little effect

Darker skin tones are typically more sensitive than lighter skin tones and prone to hyperpigmentation due to the naturally increased amount of melanin or pigment in the skin

Glucose also plays a key role, as it enters cells through GLUT1 and GLUT4, with insulin enhancing glucose uptake by promoting GLUT4 translocation to the cell membrane