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Description

where all four Cys residues within GSTP1 were mutated to Ser (V5_GSTP1-Cys15/Cys48/Cys102/ Cys170Ser, named V5_GSTP1_4XCysSer) or Ala (V5_GSTP1_4XCysAla)

Parameter fitting of IGF signaling pathway Each coefficient of the IGF signaling pathway system was optimized by fitting the experimental results of IRS-1 protein levels and Akt activity (related to pmTORC1 activity)