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A deficiency in vitamin B12 can lead to an increase in melanocyte skin cells, which may boost melanin production

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J Pineal Res 53(3):298306 Licciardello C, DAgostino N, Traini A, Recupero GR, Frusciante L, Chiusano ML (2014) Characterization of the glutathione Stransferase gene family through ESTs and expression analyses within common and pigmented cultivars of Citrus sinensis L

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doi:10.1016/j.jri.2020.103083 62

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Thus, this interplay and individual participation of MAPK signaling in steroidogenesis remains unclear

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