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List of studies Overview of EpitalonHighly Bioactive Pineal Tetrapeptide with Promising Properties Type of study: literature review Number of citations: 1 Year: 2025 Authors: Szymon Kamil Araj, Jakub Brzezik, Katarzyna Mdra-Gackowska, ukasz Szeleszczuk Journal: International Journal of Molecular Sciences Journal ranking: Q1 Key takeaways: Epitalon shows significant geroprotective and neuroendocrine effects, with potential mechanisms including antioxidant, neuro-protective, and antimutagenic effects

The cyclic structure of MT-2 makes it a more potent, non-selective agonist across the melanocortin receptor subtypes (MC1R, MC3R, MC4R, MC5R) in research models, whereas Melanotan I is comparatively more selective for MC1R

In thalassemia, the challenge is not only that blood is low, but that the process of tissue formation is chronically inefficient

The activity of microglia can be modulated by designing specific agonists or inhibitors targeting Piezo1, thereby enhancing their ability to clear A plaques