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Callier P, Calvel P, Matevossian A, Makrythanasis P, Bernard P, Kurosaka H, Vannier A, Thauvin-Robinet C, Borel C, Mazaud-Guittot S, Rolland A, Desdoits-Lethimonier C, Guipponi M, Zimmerman C, Stevant I, Kuhne F, Conne B, Santoni F, Lambert S, Huet F, Mugneret F, Jarzelska J, Faivre L, Wilheim D, Jegou B, Trainor PA, Resh MD, Antonarakis SE, Nef S: Loss of function mutation in the palmitoyl-transferase HHAT leads to syndromic 46, XY disorder of sex development by impeding hedgehog protein palmitoylation and signaling

Mice were assigned to two groups according to the injected cell type: Cas9C (control) and koSLC25A39 (knockout)

Oxidant-induced DNA damage of target cells

The results of the study revealed that wheatgrass protects the antioxidant defense system by activating antioxidant enzymes and reduced mercury-induced oxidative stress by scavenging free radical in-vivo conditions