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Nivolumab + Ipilimumab for MSI-H/dMMR Metastatic Colorectal Cancer FDA Approval Date: April 8, 2025 The FDA approved nivolumab plus ipilimumab for adults and adolescents (12 years) with unresectable or metastatic MSI-H/dMMR colorectal cancer, converting nivolumab monotherapy from accelerated to regular approval