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Escalate only after confirming tolerance and assessing initial response

Environmental and maternal dietary factors play a crucial role in ensuring normal DNA methylation in the developing embryo, suggesting that folate and B12, key factors in one-carbon metabolism, are instrumental in preventing NTDs through their effects on methylation [82]

When multiple cycles are purchased together, they run consecutively without a break between them

In some studies, telomere length rose by an average of 33.3%, though results varied between individuals, likely due to differences in baseline telomerase activity, cellular age, and other metabolic factors [4, 14]