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Description

PMID: 25 HarimotoNWangHIkegamiTTakeishiKItohSYamashitaYIet al

The experimental set-up was consistent with previously reported [43]

To prospectively test the ability of this model to design new peptides with specific activity, we used a simple optimization strategy to design 15 peptides, five in each of three different activity profiles: selective potency at GCGR, selective potency at GLP-1R or high-potency at both receptors