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By applying a 40 mg/ml dose of IGF-1 DES for 15 minutes, there was a significant 34 +/- 7% increase in the amplitude of AMPA EPSCs

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Seedorf H, Fricke WF, Veith B, Brggemann H, Liesegang H, Strittmatter A, et al

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Insulin, androgens, and estrogens tend to enhance IGF-1 secretion, whereas glucocorticoids inhibit it

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