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Although Doxorubicin cannot pass the blood brain barrier (BBB), its effect in the brain may take place through neuroinflammatory mechanisms owing to free radicals production

The inclusion criteria were a diagnosis of ASD made by a developmental pediatrician through a series of structured interviews according to the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition, DSM-5) criteria (American Psychiatric Association, 2013)

On a standard 1 mL insulin syringe, each small tick mark equals 1 unit (0.01 mL)