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2 Elevated levels of LPA, specifically unsaturated long chain acyl-LPA species, have been detected within atherosclerotic plaques and are correlated with increased expression of LPARs and dysregulated levels of enzymes that regulate LPA metabolism

Furthermore, an I53-50NP-based COVID-19 vaccine was recently approved in South Korea after successful completion of phase 1 and phase 3 studies providing a clear translational path forward for an HCV vaccine based on this platform 103

doi: 10.1172/JCI34378

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