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The precise mechanisms underlying nonimmune-mediated idiosyncratic drug-induced liver injury (DILI) remain unclear

Network localization of heterogeneous neuroimaging findings

The -cyano amide-based Michael acceptors have also been elegantly used by the Taunton group as warheads in small-molecule inhibitors to react with active site cysteines while being minimally affected by the high concentration of intracellular GSH due to the fast reaction kinetics and the mM of K d (refs 31, 32)

Jiang Y, Schiavon M, Lima LW, Tripti JRR, El Mehdawi AF, Royer S, Zeng Z, Hu Y, Pilon-Smits EAH, Pilon M (2018) Comparison of ATP sulfurylase 2 from selenium hyperaccumulator Stanleya pinnata and non-accumulator Stanleya elata reveals differential intracellular localization and enzyme activity levels