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Checkpoints in TNF-induced cell death: implications in inflammation and cancer

We found that HK2 deficiency aggravates liver I/R injury in a RIPK1 kinase-dependent manner, while overexpression of HK2 protects against liver I/R injury

Als een belangrijke intracellulaire antioxidant speelt glutathion een cruciale rol in het neutraliseren van reactieve zuurstofsoorten (ROS), zoals vrije radicalen, die cellen kunnen beschadigen en bijdragen aan verschillende gezondheidsproblemen