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Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction

Olpasiran prevents the LPA gene from forming apolipoprotein a

Further details on AF/AFL diagnostic ascertainment are described in the GBD 2021 study protocol ( Definitions of lead exposure In the GBD framework, lead exposure is quantified primarily through population-level blood lead concentration data from published surveys, national health databases, and environmental models